Production of 149Tb in nuclear reactions induced by alpha-particles
N. N. Il'inskaya, T. Yu. Malamut, A. A. Ogloblin
National Research Center "Kurchatov Institute", 123182 Moscow, Russia
Abstract
149Tb is the only known isotope decaying both by emission of
alpha-particles and positrons. This unique feature makes it possible to unite in
one radionuclide two main tools of nuclear medicine: cancer therapy by
α-particles and diagnostics using positron emission tomography. The
existing ways of production of 149Tb are far from being practical. In this paper
a simulation of the excitation functions of the nuclear reactions
151Eu(α,6n)149Tb and 153E(α,8n)149Tb was carried
out. The cross-sections in the maxima (approximately 65 and 80 MeV
correspondingly) are predicted to reach one barn, and the targets could be made
from natural Europium. Thus these reactions can serve as a basis of a new
promising technology for production of 149Tb isotope for use in a modern
field of nuclear medicine, theranostics.