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VOLUME 99 (2014) | ISSUE 6 | PAGE 409
Pore formation phase diagrams for lipid membranes
DOI: 10.7868/S0370274X14060113
Abstract
Critical lateral pressure for a pore formation and phase diagram of porous membrane are derived analytically as functions of the microscopic parameters of the lipid chains. The derivation exploits path-integral calculation of the free energy of the ensembles of semi-flexible strings and rigid rods that mimic the hydrophobic tails of lipids in the lipid bilayers and bolalipid membranes respectively. Analytical expressions for the area stretch/compressibility moduli of the membranes are derived in both models.